Novel high throughput TD–GC for breathomics workflows
Presented at IABR (International Congress for Breath Research) 2024
The use of volatile organic compounds (VOCs) in exhaled breath as biomarkers for human health and disease offers a promising, non-invasive diagnostic tool that has the potential to transform clinical practice. Breath analysis could provide a cost-effective means for large-scale screening, promoting early diagnosis and enhancing patient outcomes while reducing healthcare costs.
Thermal desorption (TD) coupled with gas chromatography-mass spectrometry (GC–MS) is recognised as the gold-standard method for analysing breath samples, however the challenge with biomarker discovery and clinical trials are the high number of samples generated and the substantial quality control demands necessitating meticulous control over background interferences from analytical instruments, sampling devices and sorbent tubes.
This poster introduces a novel cost-effective, high-throughput analytical solution to keep sorbent tube circulation flowing freely to meet the demands of on-going studies without hindering patient sample analysis.
