Skip to main content
Shopping bag
Sampling Technologies


Solid-phase microextraction (SPME) uses a small fiber coated with absorptive phase(s), to extract volatiles in either headspace or immersive modes. SPME extraction is an equilibrium process dependent on the partitioning of analytes between the sample matrix (either liquid, solid or headspace) and the absorptive phase. Analytes that become absorbed into the SPME phase are subsequently desorbed using a heated injector, before transfer to the GC column.

The simple, solvent-free nature of SPME has led to its increased popularity across a range of application areas, particularly in food and beverage analysis, clinical studies and environmental analysis. Compared with static headspace, SPME can offer improved selectivity and concentration capability, resulting from the sampling capacity of the sorptive phase. A variety of sampling phases are available to extend the applicability of SPME over a range of target analytes.

  • SPME can be easily automated with a range of different platforms
  • Using Centri®, SPME can be enhanced using a preconcentration step (SPME–trap), providing enhanced sample information
  • SPME can be used to complement HiSorb or stir-bar sorptive extraction (SBSE) and headspace analysis